CJH332H Summer 2023 Final Assessment

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Test Format

  • Multiple Choice and True/False Questions (20 Questions, 20 Marks in total)
  • Short Answer Questions (5 Questions, 20 Marks in total)

Material Covered

  • Basics of optogenetics
  • Stereotaxic surgery
  • Channelrhodopsin
  • Viral vectors
  • Calcium imaging
  • Calcium indicator
  • Genetic encoded calcium indicator (GECI)
  • Fiber photometry
  • Neurotransmitter sensors
  • Fear memory and lateral amygdala
  • Diphtheria toxin mechanism
  • Inducible Diphtheria Toxin Receptor (iDTR)
  • Designer receptor exclusively activated by a designer drug (DREADD)
  • Chemogenetics
  • Excitatory and inhibitory DREADDs
  • Long-term potentiation (LTP)
  • Long-term depression (LTD)
  • Spike-timing dependent plasticity
  • Synaptic plasticity
  • AMPAR and NMDAR in LTP
  • Risk factors of stroke
  • Transient ischemic attacks (TIA)
  • Types of stroke
  • Neuroanatomy of stroke
  • Olney’s glutamate excitotoxicity
  • Animal models of stroke
  • Repairs in stroke
  • Synucleinopathies
  • Parkinson’s disease (PD)
  • Dopamine neurons in substantia nigra
  • Animal models of PD
  • α-synuclein pathology
  • Lewy bodies
  • Multiple system atrophy (MSA)
  • Symptoms of MSA
  • Rapid eye movement (REM) sleep behaviour disorder (RBD)
  • Braak’s hypothesis

Test Content

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